- Most movies contain 600 to 700 cuts. Requiem contains over 2,000
-Director Darren Aronofsky asked Jared Leto and Marlon Wayans to avoid sex and sugar for a period of 30 days in order to better understand craving.
- Just like in The Godfather, oranges are used as a sign of disaster in this film.
-The word "heroin" is never once said by any of the characters in the film.
-Dave Chappelle was offered the role of Tyrone but turned it down.
-The prop refrigerator for the hallucination scenes melted from the inside due to the lighting elements within.
-Jared Leto lost 25 lbs. and befriended real heroin junkies from Brooklyn to prepare for his role as Harry Goldfarb.
-The overhead shot of Marion in the bathtub followed by her screaming underwater was an exact replica of a scene in the Japanese animated thriller, Perfect Blue. Darren Aronofsky bought the remake rights to the film just for that one sequence.
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